Use Case 3 – From Knowledge to Action

Support for Molecular Tumor Boards

Precision medicine already plays a major role in the care of tumor patients. For many tumors, so-called “driver mutations” can now be identified by means of molecular biological characterization in order to treat them in a targeted manner if a suitable drug is available.
In Molecular Tumor Boards (MTB), clinical information and molecular/genetic test results converge for interdisciplinary decision-making. In order to support MTBs, the MIRACUM consortium aims to improve the complex processes of quality assurance, data preparation, data analysis, data integration and information retrieval between genetic high-throughput analysis and medical therapy decisions with innovative IT solutions. In addition, clinicians will be offered decision support through efficient data visualization.

Use Case 3 of the MIRACUM consortium aims to support MTBs with IT solutions. An MTB is an interdisciplinary, cross-organ conference where clinical-pathological data and molecular findings of selected cancer patients are discussed. An interdisciplinary team of physicians and scientists from the fields of medicine, bioinformatics, medical informatics and biology votes on which therapy options promise the best chances of fighting the tumor on the basis of the available data. The application aims to identify patients without conventional or promising therapy options or with rare tumor diseases and to offer them potentially effective treatment options with a targeted therapy within the framework of precision medicine – in the context of clinical studies or individual healing trials.